A photo from open sources
Bone regeneration is based on a collagen platform with particles containing genes necessary for bone production. IN during the experiments, the gene encoding the bio patch successfully restored bones completely, up to closing wounds in the skull experimental animals.
In the course of laboratory experiments, it became clear later that this gene also stimulates the growth of new bone marrow cells. how it turned out this DNA encoding platelet growth factor, called PDGF-B, in existing bone cells in natural conditions, allows cells to produce proteins responsible for bone growth.
Previous attempts have relied on reintroduction of protein, responsible for bone growth by injection. It was very expensive, inaccessible and difficult procedure.
“We delivered the DNA directly to the cells, which creates the conditions for enhance bone regeneration, “explains Aljager Salem, Professor of Pharmaceutical College and, at the same time, co-author articles – “If you supply only protein, you need to maintain its delivery by continuous injection to maintain a dose. ”
Researchers believe the patch has several potential dental applications. For example, it may be used to restore bones in the gum area, which serves as the basis for dental implants.
This method can also be used to restore birth defects, for reconstruction of the bones of the head or face.
Testing the method on experimental animals gave encouraging results. Biopatch insertion led to faster bone growth in 14 times higher compared to existing methods.
But still, despite the achievements of science, be careful in on the eve of the ice season.
DNA
