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Canadian chemists conducted a series of experiments, as a result of which they managed to get an unusual enzyme. This enzyme allows you to make all human blood types are potentially suitable for transfusion. The donor and the recipient are known to have compatible groups, that constantly translates into a lack of necessary for one or another patient donor material.
In theory, an enzyme is able to cut off the third and red blood cells from red blood cells. the second group of antigens, making such blood look like blood of the first groups. It is known that it is possible without any negative transfusion of consequences to almost all recipients.
To create such a powerful enzyme, Canadian scientists resorted to one of the latest technologies, and personalized to the so-called directed evolution. It allows embedding in a coding enzyme gene necessary mutations. Further selection of mutant variants gives the ability to choose those that are most effective cut out antigens.
Innovative substance has been relatively successfully tested. by specialists. Canadians removed most of the antigens from the blood the second group, thereby making its red blood cells look like cells blood of the first group.
However, so far, according to scientists, it’s too early for them to celebrate victory. For effective use in practice, the enzyme must cut off absolutely all antigens, which has not yet happened. The human immune system is extremely sensitive to blood incompatibility – even a small amount of antigens causes a powerful immune response.
