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According to nydailynews, it has long been believed that chemotherapy the most effective way to fight cancer. However new research has shown that it can actually contribute disease development. Extremely aggressive therapy that kills and cancerous and healthy cells indiscriminately can lead to healthy cells will produce a protein that supports tumor growth and makes it more resistant to further treatment. Researchers from the United States have discovered this “completely unexpectedly, seeking to explain why cancer cells are so “unresponsive” inside the human body, while they die easily in the laboratory. Scientists tested the effects of the use of chemotherapy on tissue taken from a man with cancer prostate, and found “evidence of DNA damage” in healthy cells after treatment, researchers wrote in Nature Medicine. Chemotherapy works by inhibiting the reproduction of rapidly dividing cells, such as those in tumors. However, scientists have found that healthy cells damaged by chemotherapy release more protein, called WNT16B, which enhances cancer cell survival. “The increase in WNT16B was completely unexpected,” AFP said. study co-author, Peter Nelson, of the Cancer Scientific Fred Hutchinson Center in Seattle. “When the WNT16B stands out, it begins to interact with neighboring tumor cells and, invading makes them grow. And most importantly, do not give in follow-up therapy, “said Nelson. In the treatment of cancer, a tumor often react initially, but then quick repeated growth and resistance to further chemotherapy occurs. The rate of reproduction of tumor cells has been found to be increases between treatments. “Our results show that damaged benign cells … can directly help increase the kinetics of tumor growth, “the team writes. According to the researchers, they confirmed their findings by studying processes in breast tumors and ovarian cancer.
DNA Oncology